Announcements: Thanks to all for a great semester!
Syllabus: The syllabus can be found here.
Lecture notes: The lecture notes for BIOS 6312 are under construction! Updates are posted periodically.
| # | Topic | Slides | R examples |
|---|---|---|---|
| 1 | Welcome and review | Link | Link |
| 2 | Simple linear regression | Link | Link |
| 3 | Multiple linear regression | Link | Link |
| 4 | Weighted least squares | Link | Link |
| 5 | Basis expansions and splines | Link | Link |
| 6 | Regression with discrete outcomes | Link | Link |
| 7 | Regression with time-to-event outcomes | Link | Link |
| 8 | Prediction and penalized regression | Link | Link |
| 9 | Methods for clustered data | Link | N/A |
| 10 | Methods for missing data | Link | N/A |
| 11 | The bootstrap | Link | N/A |
| 12 | Nonlinear regression | Link | N/A |
| 13 | Bayesian methods | Link | N/A |
Labs: Links to this year’s labs can be found below.
| # | Date | Topic | Lab | Key |
|---|---|---|---|---|
| 1 | 01/28 | Data management in Stata | Link | Link |
| 2 | 02/01 | Two-sample testing | Link | Link |
| 3 | 02/08 | Simple linear regression | Link | Link |
| 4 | 02/15 | Multiple linear regression (I) | Link | Link |
| 5 | 02/22 | Multiple linear regression (II) | Link | Link |
| 6 | 03/01 | Binary outcome regression | Link | Link |
| 7 | 03/08 | Discrete outcome regression | Link | Link |
| 8 | 03/15 | Survival analysis | Link | Link |
| 9 | 03/29 | The elastic net penalty | Link | Link |
| 10 | 04/05 | Correlated data | Link | Link |
| 11 | 04/12 | Bayesian regression | Link | Link |
| 12 | 04/19 | Multiple imputation | Link | Link |
Problem sets and keys: This year’s collection of problems can be found here and solutions will be posted in this document. Problems will be due in batches on a biweekly basis (see below for a breakdown and for keys to last year’s assignments).
| # | Due date | Required | Optional | Key (2020) |
|---|---|---|---|---|
| 1 | 02/04 | 1, 2 | 3 | Link |
| 2 | 02/18 | 4, 5, 6, 7 | 8 | Link |
| 3 | 03/04 | 9, 10, 11 | 12 | Link |
| 4 | 03/18 | 13, 14, 15, 16 | 17 | Link |
| 5 | 04/01 | 18, 19, 20 | 21 | Link |
| 6 | 04/15 | 22, 23 | 24 | Link |
| 7 | 04/29 | 25 | 26 | Link |
Data: Data sets and documentation can be found here (you will need the password).
Exams: Prior exams given in this course are provided below.
| Description | Study guide | Exam | Key |
|---|---|---|---|
| Exam 1 (2020); In-class | N/A | Link | Link |
| Exam 2 (2020); Take-home | N/A | Link | Link |
| Exam 1 (2021); Take-home | Link | Link | Link |
| Exam 2 (2021); Take-home | Link | Link | Link |